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179 HSP60 and HSP70 in mitochondrial control, stress adaptation, and immune modulation HSP60 plays dual role in tumor promotion and suppression HSP60 exhibits context-dependent roles in cancer, acting as either a tumor promoter or suppressor depending on the malignancy type
Cloning Primers for Gibson assembly were designed using SnapGene (version 4.1.9)
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The group of nAbs requiring higher levels of occupancy for neutralization has been associated with cryptic epitopes and Env breathing
Together, these data place carnitine downstream of KG and demonstrate the necessity of the KGDD TMLHE and the de novo carnitine-synthesis pathway for resistance to DNA-damaging agents in HR-proficient models (Fig
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