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A rat model of hyperthyroidism induced by L-thyroxine injections suggested that L-carnitine might have dose-dependent protective effects against liver damage [59]
Notably, PTC cell lines with relatively low basal GPX4 expression, such as MDA-T32 and MDA T-68 cells, had a lower LC 50 compared to K1 cells with high GPX4 expression
The patients had to fill out a detailed questionnaire, undergo a clinical assessment and medical history, and give a blood sample
Normally, to avoid the harmful effects of ROS, cells upregulate their antioxidant defenses (both enzymatic and non-enzymatic) [296, 300]
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