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Whether endogenous glucocorticoid secretion as a consequence of PAMP administration contributes to the enhancing effect of PAMPs to NHO development is a current line of investigation
Sample type considerations Different biological matrices have different detection characteristics: Urine: Most common testing matrix, metabolites accumulate Blood/plasma: Shorter detection windows for most peptides Dried blood spots: Emerging method with good sensitivity Hair: Not commonly used for peptides but theoretically possible Most anti-doping testing uses urine
N Engl J Med 307(13):798800
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