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This event probably had evolutionary significance.
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CrajoinasROOricchioFTPessoaTDPachecoBPLessaLMMalnicGet al
Wenjing, H
112,113 In metastatic hormone receptorpositive breast cancer, mutations in the ligand-binding domain (LBD) of estrogen receptor 1 (ESR1), which encodes ER, contribute to treatment resistance
The type I form represents about 20% of all CGD cases and is caused by mutations in the neutrophil cytosolic factor 1 (NCF1) gene, which encodes the p47-PHOX protein
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