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In stressed cells NRF2 is released and taken from the cytoplasm into the nucleus by karyopherins (Theodore et al., 2008
It indicates that sulforaphane protects against oxidative damage by APAP by enhancing cellular antioxidant activity (Vuong et al., 2019)
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nutritionally balanced reduction diet on body composition, strength, and endurance performance in healthy young males: a randomized controlled trial
However, in the process of tumor development, tumor cells may release some FA into TME, thus affecting the function of infiltrating immune cells, such as the transition from TAM to M2 phenotype
Needs much more research
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