Changing brands of vitamin B12, forms of B12 (cyanocobalamin vs hydroxocobalamin), or switching from injections to tablets can be a solution in those (rare) cases
The volume depends on the target working concentration
The published literature is dominated by rodent models, isolated-tissue experiments and in-vitro cell assays
B12 injections are also used to treat people with malabsorption (gastrointestinal conditions that prevent proper absorption of B12 from the gut), for example, people with atrophic gastritis (stomach inflammation) and intrinsic factor deficiency (pernicious anemia) or those who have undergone surgical procedures such as gastrectomy or small bowel resection (stomach or intestine removed), autoimmune diseases, etc
This injection is for subcutaneous use only and should be taken as directed by your healthcare provider.
At Chicago Arthritis and Regenerative Medicine, we offer a range of treatment options for a variety of rheumatologic disorders including: Rheumatoid Arthritis, Psoriasis, and Ankylosing Spondylitis Osteoporosis Systemic Lupus Erythematosus Does a Cortisone Shot Really Fix Thumb Arthritis