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Experiments have provided supporting evidence for the potential of quercetin as a new candidate for the development of iron death inhibitors for the treatment of DKD by evaluating the effects of quercetin on HG-induced renal tubular epithelial cell injury and the DKD rat model (Zhang et al., 2024)

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The SURMOUNT-4 trial showed tirzepatide achieved up to 22.5% weight loss versus 16% for semaglutide at comparable 68-week endpoints, though outcomes overlap significantly depending on dose and individual factors

Results & Long-Term Maintenance Most patients begin to see noticeable changes within the first few weeks, with significant weight loss achieved over several months