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10.1637/10426-101712-Reg.1 223
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Its designed for long-term use to support weight loss and help manage chronic conditions such as type 2 diabetes and obesity
Patients with Prediabetes The SCALE Obesity and Prediabetes trial found that liraglutide 3.0 mg reduced the rate of progression from prediabetes to type 2 diabetes by 79% over 56 weeks (hazard ratio 0.21, 95% CI 0.13 to 0.34) [1]
Tirzepatide shows a statistical edge in most comparisons
This 90-day lag was implemented to account for the time required for GLP-1 RAs to exert potential neuromodulatory effects and to minimize reverse causality
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