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There are three different isocitrate dehydrogenase (IDH) enzymes in humans identified as IDH1, IDH2, and IDH3 with only the IDH3 isoform being involved in the TCA cycle

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Rybelsus and the Wegovy pill are daily tablets that demand an empty stomach and a 30-minute wait, while Foundayo drops every timing rule at the cost of less weight loss (~11% vs 15 to 21%)

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These results indicate a class effect of GLP-1RAs on neuroprotection in PD