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Since ROS-dependent DNA damage is markedly increased in myeloid cells after Bcr-Abl transformation 18 , we hypothesize that blocking dTTP and dCTP supply might exacerbate replication stress and DNA damage in Bcr-Abl-transformed cells, thereby jeopardizing cell survival
Torrejon, D
Maithili S, Karen MD, Shala D, Carly S, Sandra C, Bo L, et al
Murin R, Vidomanova E, Kowtharapu BS, Hatok J, Dobrota D (2017) Role of S-adenosylmethionine cycle in carcinogenesis
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