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and reduces fat storage
ROR 1.35, 95% CI 0.981.87, for cholelithiasis)
Table 4 condenses this protocol into a risk-adjusted induction guide, and the text below elaborates each decision node
Claims described as "according to the brand," "brand-stated," or "per brand disclosure" reflect what the brand has publicly stated and have not been independently substantiated by this publication
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The evidence from published intervention trials is consistent: T/T individuals receiving adequate 5-MTHF + B12 + B6 supplementation normalize plasma homocysteine to levels similar to C/C individuals, restore BH4 availability and endothelial function, and reduce the functional consequences of MTHFR impairment across most of the five longevity mechanisms described above
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