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Current evidence indicates that these skeletal changes are predominantly secondary to weight loss rather than to direct GLP-1 receptor agonistmediated effects on bone
& Federici, L
Correlations were assessed with Pearson correlation coefficients ( r )
As a once-weekly injection, Wegovy helps individuals with a BMI of 30 or higher, or 27 or higher with a weight-related condition, achieve their weight loss goals
IC95%: 0.71-0.87
However, when combined with GLP-1 receptor activation and the resulting insulin enhancement, the net effect is improved glycemic control rather than hyperglycemia
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