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Terrill SJ, Jackson CM, Greene HE, Lilly N, Maske CB, Vallejo S, et al
The therapeutic approach for HCC remains focused on curative treatments for early stages (resection, ablation, transplantation) or palliative systemic therapies for advanced disease (tyrosine kinase inhibitors [TKIs] and VEGF inhibitors) and immunotherapies (i.e., programmed death 1 [PD-1]/programmed cell death-ligand 1 [PD-L1] inhibitors and anti-cytotoxic T-lymphocyte-associated protein 4 [CTLA-4] antibodies) (Sadagopan et al., 2024
Metabolic Support: Semaglutide is a GLP-1 receptor agonist that helps regulate blood sugar levels, improve insulin sensitivity, and promote weight loss by reducing appetite and enhancing satiety signals in the brain
10.1093/eurheartj/ehab644 89
Because both berberine and semaglutide can cause gastrointestinal side effects and lower blood sugar , it may be wise to take them at different times
One study found that 20% of Hashimotos disease patients have gastric autoimmunity, including pernicious anemia
