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Molecular docking The protein structures of p53 (PDB ID: 8E7A) and HDAC7 (PDB ID: 3C0Y) were obtained from the Protein Data Bank ( Ligands and receptor proteins were preprocessed using AutoDock Tools 1.5.6, and molecular docking was performed using AutoDock Vina
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It wide spectrum of activity allows retatrutide to bind to several difference incretin receptors and produce specific effects as follows
Although multiple metabolic parameters were assessed, statistical adjustment for multiple comparisons was applied to reduce the risk of type I error
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