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8 (download XLSX Statistical Source Data

The enzyme isoform, prostaglandin H 2 synthase-2, may mediate vascular dysfunction under oxidative stress conditions

Amino acids are the structural units that make up proteins

So, in summary: FOXO4-DRI appears to represent the next-generation senolytic, offering improved specificity, but it is still earlier stage than many small-molecule senolytics or repurposed drug combinations

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MckeeACSteinTDHuberBRCraryJFBieniekKDicksonDet alChronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts