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This benefit persisted for up to six months in a multicenter, randomized, placebo-controlled study involving 240 patients with knee osteoarthritis
While direct evidence linking CYP51A1 to pyroptosis is currently lacking, its emerging role in shaping innate immune responses highlights the need to further investigate whether CYP51A1 functions as a metabolic checkpoint that fine-tunes inflammasome activation and pyroptotic outcomes in inflammatory diseases
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