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Clinical trial data shows diarrhea rates of 19-23% across doses, with nausea remaining the predominant side effect at 24-31%

(which operates as Hims and Hers) Location: San Francisco, CaliforniaStore Websites: and Letter Date: September 9, 2025FDA Department issuing Warning: Center for Drug Evaluation and Research (CDER)Types of Products Sold: Prescribes and sells compounded semaglutide, tirzepatide and other compounded productsType of Warning: Unlawful Sale of Unapproved and Misbranded Drugs to United States Consumers Over the InternetFDA Warning: The website makes false claims about compounded drug products, including: Same active ingredient as Ozempic and Wegovy and Clinically proven ingredients. The claims imply that the products are the same as an FDA-approved product when they are not

10.1038/tp.2013.83 251

Bottom line: A healthcare provider must perform a thorough screening of your medical history and current medications before considering these two treatments together

Previous data demonstrated that activation of GLP-1R could alleviate neuropathic pain, cancer pain and diabetic neuropathy [20]