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Ipragliflozin, one of the SGLT2 inhibitors, was the first such agent to obtain regulatory approval in Japan on January 17, 2014

The dual role of NRF2 in colorectal cancer: targeting NRF2 as a potential therapeutic approach

101.3 Measuring What Matters in Primary Care: Health-Related Quality of Life and Its Predictors Among Users of Public Primary Care Clinics in Singapore Using the EQ-5D-5L Ling Jie Cheng 1 , Qin Xiang Ng 2 , Guang Jie Justin Lee 2 , Gerald Choon Huat Koh 3 , Nan Luo 3 1 National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK, 2 Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore, 3 Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :101.3 Aims Health-related quality of life (HRQoL) is increasingly recognised as a key outcome in healthcare delivery, particularly in primary care settings where multimorbidity is rising

The time horizon for base case analysis was set at 40 years, which corresponded to the mean age of the simulated cohort and was deemed sufficient to capture lifetime cost-effectiveness