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This approach helps minimize common gastrointestinal side effects such as nausea, vomiting, and diarrhea, which are more likely when starting at higher doses

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Especially in PDLSC, Ex-4 has also proven to activate MAPK and WNT-signaling [19, 21, 24] as well as Hedgehog/Gli1-1 and nuclear factor kappa B (NF-B) signaling, thus promoting osteogenic differentiation [15, 17, 21, 24, 26, 38]

The polymer syringe also features a user-friendly design, reducing the risk of administration errors

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