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performed an unbiased quantitative proteomics and pathway network analysis that identified increased carnitine-O-octanoyltransferase (CROT) levels in calcifying primary human coronary artery smooth muscle cells (SMCs)

PDA Journal of Pharmaceutical Science and Technology, 70 (3) 218-229

But the broader physiology of the person may deserve a more central place in our clinical reasoning

As such, liver disease may lead to increased ROS production and, subsequently, increased peroxidation of lipid membranes and inflammatory factors production, leading to hepatocyte injury and cell death (65, 66)

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