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The most common protocol involves evening administration to align with the bodys natural GH secretion pattern

If evenings are when you overeat, an afternoon injection puts peak levels at dinnertime

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However, starting with an SGLT2 inhibitor or a GLP-1 RA in an individual who is intolerant to metformin (primarily diarrhea) is a good choice, and even in the future we may see large diabetes organizations recommending these two classes as first line therapy once they get less expensive.

It works by signalling to the brain that you feel full, slowing how quickly the stomach empties, and helping control blood sugar after eating