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By adding a stimulant like phentermine to a GLP-1 regimen, a provider may be able to reset the appetite signals
The incidence of symptomatic gastroparesis is approximately 14 per 100,000 person-years, but subclinical delayed emptying may be more common
Both produce consequential weight loss, but they differ in dosing, side effect profiles, and clinical data
S.ThitilertdechaP.KabraA.TencomnaoT.et al (2021)
Almost none of them give the same careful attention to vitamin D, and that oversight may be quietly working against everything their protocol is
Meta-analyses from multiple randomised controlled trials of GLP-1s in T2D populations, many with established CKD or very high cardiovascular risk, suggest roughly a 20% relative reduction in kidney outcomes, supporting a class effect
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