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19,96 Restoration of SIRT1 activity suppresses lipid synthesis, improves oxidation capacity, and reestablishes lipid clearance, supporting therapeutic strategies aimed at metabolic reprogramming in MASLD
The second mechanism is characterized by the modulation of intracellular calcium, which seems to function as a trigger for rapid insulin exocytosis and complements the amplification phenomena [8]
Zhang, 2024)
Lancet 2023;402:72030.ArticlePubMed 11