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Syndecan A family of homodimeric transmembrane proteoglycans that serve as receptors to the extracellular matrix (ECM) and growth factors via their extracellular glycosaminoglycan chains, and which contain small cytoplasmic domains with interaction sites for Src and Fyn tyrosine kinases and the PDZ (Post-synaptic-density-95/disc large tumour suppressor/zonula occludens 1) proteinprotein interaction domain

Most patients benefit from loading dose packages consisting of 4-6 sessions over a concentrated period

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