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Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models
GLP-1 inhibits glucagon secretion under hyperglycaemic conditions and thereby improves glycaemia
GLP-1s are predicted to become the best-selling drug class of 2024 (inclusive of diabetes and obesity) 2 The late-stage obesity pipeline is dominated by big pharma, and 8 of the top 20 pharma companies have a clinical stage asset in development The obesity pipeline has almost tripled in size since June 2023, and there are up to 6 new U.S
Access and affordability are significant challenges, as are governmental policies, such as the current prohibition on Medicare coverage for weight loss medications in the US, restrict availability for many individuals who could benefit from these therapies
Blood pressure should be rechecked at the 8-week visit
Precautions During Treatment Monitor EPO Sensitivity: As anemia improves, the nephrology team must be prepared to down-titrate EPO doses to prevent polycythemia (excessively high red blood cell counts)
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