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Turns out, your bod doesnt absorb every little microgram of B12 in your supplement (youll prob pee out the rest), so higher doses can help improve B12 levels

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Free Radic Biol Med 221, 257-260

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Fourth, residual confounding remains a fundamental limitation, as crucial variables including socioeconomic status, educational attainment, baseline cognitive reserve, lifestyle factors, and genetic risk are often inadequately captured or adjusted for in claims-based databases