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Common Misconceptions Future Research Directions Useful future work includes standardized definition of the exact copper complex, independent analytical replication, improved pharmacokinetic and toxicology characterization, controlled comparisons between GHK and GHK-Cu, reproducible gene-expression studies, and appropriately designed human research
Mol Cancer Ther
63 suggested that arbutin primarily relies on the hydroxyphenyl part to form - stacking with histidines around the metal site, stabilizing its binding
Bannai M, Kawai N
Jain, S
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