The three main genetic subtypes are represented by paternal 15q11.2-q13 deletion, maternal uniparental disomy 15, and imprinting defect
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First, as with other studies using electronic health databases, the analysis of the TriNetX database relies heavily on diagnosis codes, which may introduce both misclassification bias due to coding errors and ascertainment bias from the underrepresentation of mild cases
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Many user reports describe meaningful reductions in perceived recovery time, sometimes characterized as "cutting healing in half." Those claims are anecdotal rather than clinically validated, and outcomes vary by injury severity, age, sleep, nutrition, and rehab adherence