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This bile acid medication can reduce cholesterol saturation in bile and has been shown in studies of bariatric surgery and very low calorie diets to decrease gallstone formation during rapid weight loss
TRIUMPH-4 enrolled 445 adults with obesity or overweight combined with knee osteoarthritis and tracked them for 68 weeks
10.1007/s11427-023-2532-5 27 LiL.ZhaoY.DingY.GuoL.DaiR.ChenA.et al (2025)
Some people tolerate it fine
10.1016/j.bmcl.2018.02.013 286
Some people may also experience vomiting, which can be more distressing
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