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Pharmacotherapy is considered only when lifestyle interventions alone have been insufficient, and then as an adjunctnot replacementto continued lifestyle modification

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"If you need to drop the dose and then expand the frequency, to taking it maybe once a month, once every other week, the key is keeping you at that healthy weight in the safest, most efficacious way we can do it." Editor's note: This story was originally published on May 19, 2023.