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Excess H 2 O 2 can be detoxified by Asc, GSH, CAT and APX activity in peroxisomes and the cytosol, by Asc, GSH and APX activity in chloroplasts, while in vacuoles only Asc is available as a reductant and guaiacol-type peroxidase (EC 1.11.1.7) activity aids in scavenging excess H 2 O 2 (Fig

(PubMed) McDonnell MG, Archbold GP

Avoid combining with NSAIDs, which may counteract its healing effects

This isnt practical for individuals who suffer from chronic B12 deficiency or frequently deplete the entirety of their B12 stores

High supplemental doses may cause nerve damage and skin lesions, but getting vitamin B6 from food doesnt appear to have any negative effects

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