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Bariatric surgery Studies in participants with overweight and obesity have also investigated the effects of weight-loss surgeries such as Roux-en-Y gastric bypass (RYGB), bariatric surgery, massive weight loss, or sleeve gastrectomy

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GLP-1 medicines in neuro- and cardiovascular inflammation Microglia secrete pro-inflammatory cytokines upon activation, stimulating nearby reactive astrocytes and amplifying local neuroinflammation

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This endogenous activation provides sustained cellular protection compared to direct free radical scavenging by exogenous antioxidants