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They have not been shown to reliably reduce DHT production or block androgen receptors in the same way as treatments specifically intended to address androgen-related hair loss

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For example, animal studies have shown that GLP-1 receptor agonists can reduce pain signaling, including the activity of calcitonin gene-related peptide, and lower neuroinflammation both of which are key players in the development of migraine

(1984): DSIP showed analgesic properties in chronic pain patients, with effects mediated through opioid receptor interactions

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