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As we age, collagen production decreases, leading to the formation of wrinkles
Free Cu2+ is toxic (Fenton reactions, hydroxyl radicals), but the GHK-Cu complex is stable, diffusible and delivers copper in a targeted manner to copper-dependent metalloenzymes: lysyl oxidase (collagen/elastin crosslinking), Cu/Zn superoxide dismutase (SOD1, antioxidant defence), tyrosinase (controlled melanogenesis), dopamine-beta-hydroxylase
doi:10.1001/archpedi.160.9.933
This stability explains the positive results of BPC-157 in gastrointestinal repair models (ulcers, fistulas, colitis)
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