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Antitumor activity of the IGF-1/IGF-2neutralizing antibody xentuzumab (BI 836845) in combination with enzalutamide in prostate cancer models

At BHRC, our physicians often combine it with CJC-1295 (no DAC) for synergistic effectsmaximizing natural GH production while maintaining physiologic pulsatile release patterns

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It has demonstrated particular efficacy in reducing visceral adipose tissue

For example, ALK fusions in NSCLC represent actionable alterations, with multiple ALK inhibitors demonstrating efficacy in ALK-positive tumors

The responsible path is to follow the data closely, give patients honest assessments, and be ready when the evidence catches up to the promise