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The only human data available comes from a 2025 pilot study by Lee and Burgess, published in Alternative Therapies in Health and Medicine

While the RESET Methods address structural, neurological, and functional correction, the patch supports cellular repair, reduces inflammation, and enhances tissue recovery

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Electronic clinical outcome assessment (eCOA) platforms, such as Medable and Clinical Ink, enable patients to report symptoms and QoL metrics in a timely and structured manner

The addition of B12 to their treatment protocol may help lessen their discomfort and improve their quality of life