which has less side effects semaglutide or tirzepatide Tirzepatide vs Semaglutide: what's the difference? 👀 Both are game-changers in metabolic medicine — but Semaglutide vs. Tirzepatide: Which Weight

In the diabetes TRIUMPH-2 trial, reported side effects included: Diarrhea (around 27 to 34 percent of participants, depending on the dose) Nausea (14 to 28 percent) Constipation (14 to 17 percent) Decreased appetite (6 to 17 percent) Vomiting (6 to 16 percent) In the TRIUMPH-3 trial for adults with severe obesity and heart disease, participants reported: Diarrhea (around 24 to 30 percent of participants, depending on the dose) Nausea (22 percent) Constipation (16 to 18 percent) Decreased appetite (14 to 15 percent) Hyperglycemia, or high blood sugar (3 to 4 percent) The high rates of diarrhea surprised Ali

Sulfur burps typically appear within the first few weeks of starting the medication or increasing the dose and usually resolve within 6-8 weeks

If tolerated, increase to 7 mg daily

Clinical trials and meta-analyses have shown that these drugs significantly improve glycemic control, reduce blood pressure, and positively impact lipid profiles, even in patients without diabetes

Patients do report fewer side effects with tirzepatide, though this is variable, and I have had patients with no side effects on both medications, says Mir Ali, MD, board-certified general surgeon, bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, California

The syringe goes directly from your hand into the sharps container without recapping