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Remarkably, astrocytes can exert opposing effects on different synaptic inputs depending on the adenosine receptor subtype

His PHQ-9, a marker for depression severity, decreased dramatically over the course of the fast

Evidence of benefit from such an approach is provided by a study in trauma patients (47), which showed that a high-dose antioxidant cocktail of vitamin C (1000 mg every 8 hrs), vitamin E (1000 units every 8 hrs), and selenium (200 g daily) for 7 days was associated with a significant decline in cases of respiratory failure and ventilator dependence (47)

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Stress increases cortisol, which initially suppresses inflammation but ultimately leads to cortisol resistance and rebound inflammation