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Food and Drug Administration , 2025
Biological Psychiatry, 54(5), 573583
You can also help increase your output during low intensity workouts so even those smaller sessions support your gains
This pattern is reported across forums and is consistent with IGF-1's known effects on intracellular hydration and protein synthesis through PI3K/Akt/mTOR (Yoshida & Delafontaine, 2020)
They may help muscle growth indirectly when pain, soreness, or soft tissue strain prevents consistent training
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