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In preclinical studies, the drug has shown strong anti-tumor activity and survival advantage in AML, DLBCL, cALL, and Burkitt lymphoma tumor models

The precursor for acetylation modification is acetyl-CoA, and classical acyltransferases and deacetylases are believed to catalyze all acetylation modifications and deacetylation modifications, including non-classical acyltransferases such as dihydrolipoamide S -acetyltransferase (DLAT) at the same time (Fig

J Pharmacol Exp Ther 324(3):970976

The storage of glycogen is also hampered

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Anti-citrullinated protein antibody (anti-CCP/ACPA) positivity captured separately under M05.A (FY2026) indicates a more aggressive disease course and warrants distinct documentation