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they also helped patients lose weight
A series of five case reports of patients with chronic constipation-predominant irritable bowel syndrome (IBS-C) treated with fecal microbiota transplant describe immediate remission in all five cases
GLP-1 (semaglutide or tirzepatide) Therapy in Older Adults: Balancing Benefit & Risk Beyond Age 65 Joshua Silva, MD Dec 12, 2025 4 min read Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD Last clinically updated: December 2025 Many discussions about GLP-1 medications in older adults come from friends, family, or acquaintances , as well as online forums, news stories, and social media posts
Exercise takes care of everything else
Animal research has shown issues like reduced fetal growth and developmental changes when GLP-1 medications were used during pregnancy, which is why experts advise using reliable contraception while on treatment and stopping early when planning for pregnancy
[48-51] In parallel with achieving the A1c goal, it is also recommended that GLP-1RA or SGLT2i be included for patients with T2D with or at high risk of ASCVD to reduce cardiorenal risk, irrespective of A1c
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