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The most common causes of dementia include: Alzheimer's disease Vascular dementia Parkinson's disease Dementia with Lewy bodies Frontotemporal dementia Severe head injury Other less common causes include: Huntington's disease Leukoencephalopathies, diseases that affect the deeper, white-matter brain tissue Creutzfeldt-Jakob disease, a rare and fatal condition that destroys brain tissue Some cases of multiple sclerosis (MS) or amyotrophic lateral sclerosis (ALS) Multiple-system atrophy, a group of degenerative brain diseases that affect speech, movement, and autonomic function Infections such as late-stage syphilis Although all types of dementia are progressive, the term progressive dementia refers to dementias that happen rapidly, over the course of weeks or months