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In practice, microdosing generally refers to one of three approaches: Sub-therapeutic dosing: Using doses below 2.5 mg weekly (often 0.5 mg to 1.5 mg) Extended low-dose maintenance: Staying at the 2.5 mg initiation dose indefinitely rather than escalating Split dosing: Dividing a standard dose into smaller, more frequent administrations (such as splitting a weekly dose into twice-weekly injections ) Each approach produces different pharmacokinetic profiles and potentially different anti-inflammatory effects

The risk of gastrointestinal bleeding with naproxen is increased in those taking anticoagulants, antiplatelets, SSRIs/SNRIs, or corticosteroids, and in those aged over 65 or with a history of peptic ulcer disease

GLP-1 receptor agonists are not recommended during pregnancy due to potential risks to the fetus

Deciding if or which medicine is right for you will depend on different factors, which well assess during your consultation