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This underscores the key issue: a trial powered to identify and confirm efficacy in specific, responsive genetic subsets would be highly complex and require substantial patient numbers to stratify by mutation type

Like the original capsule version, which was approved in 2017 for tardive dyskinesia and in 2023 for chorea in Huntingtons, Ingrezzas sprinkle formulation comes in 40-mg, 60-mg and 80-mg doses but is designed to be opened and sprinkled on soft foods