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In addition, DPP-4i can alleviate vascular inflammation in hypertension by regulating inflammatory responses and improving vascular endothelial function, thereby reducing the incidence of cardiovascular complications

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The GIR increased from 3.21 to 5.16 mg min1 kg1 (p 3 major US claims databases (Medicare, Optum, MarketScan

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286 Kholodenkos Modular Response Analysis (MRA) and Boolean network simulations can identify minimal intervention setscombinatorial targets whose simultaneous inhibition destabilizes the adaptive network, precluding escape and restoring vulnerability