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It reduced pro-inflammatory cytokines (TNF-, IL-6, IL-1), chemokines, adhesion molecules and oxidative stress, while upregulating the expression of neurotrophic factors (neuritin and NGF) [11]
However, it is important to note that oral supplements may not be as readily absorbed as B12 shots
Shulman, M., Miller, A., Misher, J., & Tentler, A
2% of patients receiving placebo
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