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However, we found low heterogeneity between the five trials in all-cause mortality (I 2 = 22%) (Figure 2) and detected no heterogeneity between the two trials reporting heart failure (I 2 = 0%), unstable angina (I 2 = 0%), and myocardial reinfarction (I 2 = 0%) (Figure 3)

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All purified RNA samples were diluted and adjusted to 400 ng/l to ensure equal amounts of cDNA template for quantification of mRNA abundance