The weight loss timeline for GLP-1 peptides gives you a reference for expected progress rates
Conditions like pernicious anaemia (an autoimmune condition affecting a protein called intrinsic factor vital for B12 absorption), stomach issues (such as from reduced stomach acid or certain medications like proton pump inhibitors), intestinal disorders (like Crohns disease or coeliac disease), or even surgical removal of parts of the small intestine (e.g., gastric bypass surgery) can prevent proper absorption
It has gained research interest due to its potential in promoting hair growth and inhibiting skin aging[1]
human bioavailability is unknown Subcutaneous injection Human subcutaneous bioavailability and pharmacokinetics are unknown Factor Convenience Oral capsules No mixing or syringe math Subcutaneous injection Requires reconstitution, sterile supplies, and injection-site planning Factor Evidence limits Oral capsules No controlled human dose, benefit, or safety trial Subcutaneous injection No controlled human dose, benefit, or safety trial Factor Can the amounts be treated as equal
To avoid the burden of frequent IM injections, SQ administration of 1 mg OHCbl was initiated using a subcutaneous catheter device together with a portable infusion pump
Advantages : Provides precise measurement markings, making it easier to measure and administer small, correct doses of B12