Many patients on semaglutide develop B12 deficiency over time because reduced food intake means reduced B12 absorption from dietary sources
GLP-1 use is safe and effective with many pre-existing conditions with the exception of the following: Currently pregnant Currently breastfeeding Currently being treated for cancer Active eating disorder Active gallbladder disease Active substance abuse or dependency Type 1 diabetes Bariatric surgery (within the past 18 months) Pancreatitis within the past 6 months, or a history of pancreatitis caused by taking a GLP-1 Personal or family history of medullary thyroid cancer or MEN syndrome Personal history of Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Please note that you will pay the manufacturer directly for the medication
Slowing NNMT production may help prevent age-related muscle loss and promote muscle repair (having muscle is essential for maintaining a healthy metabolism and burning fat efficiently)
In fact, among over 14,500 participants across multiple studies assessing the risk of thyroid cancer incidence and the use of semaglutide (the active ingredient in GLP-1 agonists), the risk of thyroid cancer was less than 1%
This effect is mediated through vagal nerve pathways and direct GLP-1 receptor activation in the gastrointestinal tract
