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Among generations, Gen Z again stood out: 88% reported improved impulse control, compared to 80% of millennials, 77% of Gen X, and 71% of baby boomers

Another trial, SOUL (NCT03914326), has now been initiated to overcome the shortcomings of PIONEER 6 with a primary endpoint focused at proving CV superiority vs placebo

You get clear guidance on how to manage possible side effects and how to keep the weight off long-term, even after you stop the medication

Reducing body weight triggers adaptive mechanisms to prevent starvation

Across cohorts, 48 weeks of retatrutide reduced liver fat by 50% or greater in 43-100% of participants and 70% or greater in 22-86%

Previous GLP-1 tolerance often predicts tolerance of related compounds